| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50179259 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_325587 (CHEMBL860170) |
|---|
| Ki | 1.01±n/a nM |
|---|
| Citation |  Berardi, F; Ferorelli, S; Abate, C; Pedone, MP; Colabufo, NA; Contino, M; Perrone, R Methyl substitution on the piperidine ring of N-[omega-(6-methoxynaphthalen-1-yl)alkyl] derivatives as a probe for selective binding and activity at the sigma(1) receptor. J Med Chem48:8237-44 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 25307.17 |
|---|
| Organism: | Cavia porcellus (Guinea pig) |
|---|
| Description: | Q60492 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
|
|
|
|---|
| BDBM50179259 |
|---|
| n/a |
|---|
| Name | BDBM50179259 |
|---|
| Synonyms: | 1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)butyl)piperidine hydrochloride | CHEMBL537842 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H31NO |
|---|
| Mol. Mass. | 301.4662 |
|---|
| SMILES | COc1ccc2C(CCCCN3CCCCC3)CCCc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
