| Reaction Details |
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 | Report a problem with these data |
| Target | Oxytocin receptor |
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| Ligand | BDBM50177595 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_334047 (CHEMBL861269) |
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| IC50 | 12±n/a nM |
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| Citation |  Failli, AA; Shumsky, JS; Steffan, RJ; Caggiano, TJ; Williams, DK; Trybulski, EJ; Ning, X; Lock, Y; Tanikella, T; Hartmann, D; Chan, PS; Park, CH Pyridobenzodiazepines: a novel class of orally active, vasopressin V2 receptor selective agonists. Bioorg Med Chem Lett16:954-9 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxytocin receptor |
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| Name: | Oxytocin receptor |
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| Synonyms: | OT-R | OXYR_RAT | Otr | Oxtr | Oxytocin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42889.28 |
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| Organism: | RAT |
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| Description: | Oxytocin OXTR RAT::P70536 |
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| Residue: | 388 |
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| Sequence: | MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACV
LLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD
VNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETS
VSKKSNSSTFVLSRRSSSQRSCSQPSSA
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| BDBM50177595 |
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| n/a |
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| Name | BDBM50177595 |
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| Synonyms: | (2S)-5-amino-2-{[(2S)-1-{[(4R,7S,10S,13S,16R)-13-[(2S)-butan-2-yl]-7-(carbamoylmethyl)-16-[(4-ethoxyphenyl)methyl]-10-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)pentanamide | Atosiban | CHEMBL382301 | ChEMBL_332615 |
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| Type | Small organic molecule |
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| Emp. Form. | C43H67N11O12S2 |
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| Mol. Mass. | 994.189 |
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| SMILES | CCOc1ccc(C[C@H]2NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)[C@@H](C)CC)[C@@H](C)O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O)cc1 |r| |
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| Structure | 
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