| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteine protease |
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| Ligand | BDBM50286441 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_336666 (CHEMBL862349) |
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| IC50 | 10±n/a nM |
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| Citation |  Desai, PV; Patny, A; Gut, J; Rosenthal, PJ; Tekwani, B; Srivastava, A; Avery, M Identification of novel parasitic cysteine protease inhibitors by use of virtual screening. 2. The available chemical directory. J Med Chem49:1576-84 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteine protease |
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| Name: | Cysteine protease |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42630.50 |
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| Organism: | Leishmania donovani |
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| Description: | ChEMBL_430130 |
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| Residue: | 394 |
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| Sequence: | MATSRAALCAVAVVCVVLAAACAPARAIYVGTPAAALFEEFKRTYRRAYGTLAEEQQRLA
NFERNLELMREHQARNPHARFGITKFFDLSEAEFAARYLNGAAYFAAAKQHAGQHYRKAR
ADLSAVPDAVDWREKGAVTPVKNQGACGSCWAFSAVGNIESQWARAGHGLVSLSEQQLVS
CDDKDNGCNGGLMLQAFEWLLRHMYGIVFTEKSYPYTSGNGDVAECLNSSKLVPGARIDG
YVMIPSNETVMAAWLAENGPIAIGVDASSFMSYQSGVLTSCAGDALNHGVLLVGYNTTGG
VPYCVIKNSWGEDWGEKGYVRVAMGLNACLLSEYPVSAHVPQSLTPALTASGNFCEACWT
VMLHRILSVLKTNGWLLGRRPSARWREDGARGGQ
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| BDBM50286441 |
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| n/a |
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| Name | BDBM50286441 |
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| Synonyms: | (S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylamino)-4-methyl-pentanoic acid (1-formyl-4-guanidino-butyl)-amide | (S)-2-Acetylamino-4-methyl-pentanoic acid [(R)-1-((S)-1-formyl-4-guanidino-butylcarbamoyl)-3-methyl-butyl]-amide | (S)-2-Acetylamino-4-methyl-pentanoic acid [(S)-1-((S)-1-formyl-4-guanidino-butylcarbamoyl)-3-methyl-butyl]-amide | (S)-2-[(S)-2-((S)-2-Acetylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-5-guanidino-pentanoic acid | (S)-2-acetylamino-4-methyl-pentanoic acid [(S)-2-(1-formyl-4-guanidino-butylamino)-4-methyl-pentanoyl]-amide | 2-Acetylamino-4-methyl-pentanoic acid [1-(1-formyl-4-guanidino-butylcarbamoyl)-3-methyl-butyl]-amide | Ac-LLR-CHO | Ac-Leu-Leu-Arg-H | CHEMBL129157 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H38N6O5 |
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| Mol. Mass. | 442.5529 |
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| SMILES | CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |
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| Structure | 
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