| Reaction Details |
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 | Report a problem with these data |
| Target | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
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| Ligand | BDBM50135169 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_361103 (CHEMBL859169) |
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| Ki | 2800±n/a nM |
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| Citation |  Tasdemir, D; Lack, G; Brun, R; Rüedi, P; Scapozza, L; Perozzo, R Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. J Med Chem49:3345-53 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
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| Name: | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
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| Synonyms: | Fatty acid synthase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26222.50 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_983601 |
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| Residue: | 230 |
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| Sequence: | MRFLIIHIAVIVLPFVLMIDVKRENSFFLRHSPKRLYKKADYNNMYDKIIKKQQNRIYDV
SSQINQDNINGQNISFNLTFPNYDTSIDIEDIKKILPHRYPFLLVDKVIYMQPNKTIIGL
KQVSTNEPFFNGHFPQKQIMPGVLQIEALAQLAGILCLKSDDSQKNNLFLFAGVDGVRWK
KPVLPGDTLTMQANLISFKSSLGIAKLSGVGYVNGKVVINISEMTFALSK
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| BDBM50135169 |
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| n/a |
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| Name | BDBM50135169 |
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| Synonyms: | (-)-Catechin gallate | (2S,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate | 3,4,5-Trihydroxy-benzoic acid (2S,3R)-2-(3,4-dihydroxy-phenyl)-5,7-dihydroxy-chroman-3-yl ester | CHEMBL129451 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18O10 |
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| Mol. Mass. | 442.3723 |
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| SMILES | Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H](Oc2c1)c1ccc(O)c(O)c1 |
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| Structure | 
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