Ki Summary

Reaction Details

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Target

Oligopeptide transporter small intestine isoform

Ligand

BDBM50169125

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_363882

IC50

280000±n/a nM

Citation

Vig BS; Stouch TR; Timoszyk JK; Quan Y; Wall DA; Smith RL; Faria TN Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding. J Med Chem 49:3636-44 (2006) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Oligopeptide transporter small intestine isoform

Name:

Oligopeptide transporter small intestine isoform

Synonyms:

Intestinal H(+)/peptide cotransporter | Oligopeptide transporter, small intestine isoform | Peptide transporter 1

Type:

PROTEIN

Mol. Mass.:

78818.07

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1488839

Residue:

708

Sequence:

MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFV
ALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPV
HVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTII
TPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCI
GFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQ
GSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKK
MAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGP
MSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQK
PEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQ
PNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSV
TGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVC
VIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM

BDBM50169125

n/a

Name

BDBM50169125

Synonyms:

(S)-6-Amino-2-((S)-2-amino-propionylamino)-hexanoic acid | 6-Amino-2-(2-amino-propionylamino)-hexanoic acid | Ala-Lys | CHEMBL191057

Type

Small organic molecule

Emp. Form.

C9H19N3O3

Mol. Mass.

217.2655

SMILES

C[C@H](N)C(=O)N[C@@H](CCCCN)C(O)=O

Structure