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TargetDelta-type opioid receptor
LigandBDBM50190368
Substrate/Competitorn/a
Meas. Tech.ChEMBL_376241 (CHEMBL869294)
Ki 2100±n/a nM
Citation Zhang, QKeenan, SMPeng, YNair, ACYu, SJHowells, RDWelsh, WJ Discovery of novel triazole-based opioid receptor antagonists. J Med Chem49:4044-7 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Delta-type opioid receptor
Synonyms:D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50190368
n/a
NameBDBM50190368
Synonyms:1-[(3-naphthalen-2-yl)-(1,2,4-triazol-4-yl) ]-3-phenol | CHEMBL379717
TypeSmall organic molecule
Emp. Form.C18H13N3O
Mol. Mass.287.3153
SMILESOc1cccc(c1)-n1cnnc1-c1ccc2ccccc2c1
Structure
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