| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
|---|
| Ligand | BDBM50190361 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_376243 (CHEMBL869298) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Zhang, Q; Keenan, SM; Peng, Y; Nair, AC; Yu, SJ; Howells, RD; Welsh, WJ Discovery of novel triazole-based opioid receptor antagonists. J Med Chem49:4044-7 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kappa-type opioid receptor |
|---|
| Name: | Kappa-type opioid receptor |
|---|
| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 42648.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P41145 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
|
|
|
|---|
| BDBM50190361 |
|---|
| n/a |
|---|
| Name | BDBM50190361 |
|---|
| Synonyms: | 1-[3-(3-biphenyl)-5-N,N-dimethylamino-(1,2,4-triazol-4-yl) ]-3-phenol | CHEMBL209152 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H20N4O |
|---|
| Mol. Mass. | 356.4204 |
|---|
| SMILES | CN(C)c1nnc(-c2cccc(c2)-c2ccccc2)n1-c1cccc(O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
