| Reaction Details |
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 | Report a problem with these data |
| Target | 2-dehydropantoate 2-reductase |
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| Ligand | BDBM50370755 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_382751 (CHEMBL854530) |
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| Kd | 6900000±n/a nM |
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| Citation |  Ciulli, A; Williams, G; Smith, AG; Blundell, TL; Abell, C Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods. J Med Chem49:4992-5000 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 2-dehydropantoate 2-reductase |
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| Name: | 2-dehydropantoate 2-reductase |
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| Synonyms: | Ketopantoate reductase | PANE_ECOLI | apbA | panE |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33866.35 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_382751 |
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| Residue: | 303 |
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| Sequence: | MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETDGSIFNESLTANDPDF
LATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGTIEELQNIQQPLLMGTTTH
AARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVLPDVAWHNNIRAELWRKLAVN
CVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIEREGHHTSAEDLRDYVMQVIDATAE
NISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVPENTRLFEMVKRKESEYERIGTGLP
RPW
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| BDBM50370755 |
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| n/a |
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| Name | BDBM50370755 |
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| Synonyms: | Myprozine | NICOTINAMIDE_ADENINE_DINUCLEOTIDE | Natacyn | Natamycin | Pimafucin | Pimaricin | Tennecetin |
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| Type | Small organic molecule |
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| Emp. Form. | C33H47NO13 |
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| Mol. Mass. | 665.7252 |
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| SMILES | C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@@](O)(C[C@H](O)[C@H]3C(O)=O)C[C@@H](O)C[C@H]3O[C@@H]3\C=C\C(=O)O[C@H](C)C\C=C\C=C\C=C\C=C\2)[C@@H](O)[C@@H](N)[C@@H]1O |r,t:27,35,37,39,41| |
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| Structure | 
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