| Reaction Details |
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 | Report a problem with these data |
| Target | 2-dehydropantoate 2-reductase |
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| Ligand | BDBM18137 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_382751 (CHEMBL854530) |
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| Kd | >5000000±n/a nM |
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| Citation |  Ciulli, A; Williams, G; Smith, AG; Blundell, TL; Abell, C Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods. J Med Chem49:4992-5000 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 2-dehydropantoate 2-reductase |
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| Name: | 2-dehydropantoate 2-reductase |
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| Synonyms: | Ketopantoate reductase | PANE_ECOLI | apbA | panE |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33866.35 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_382751 |
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| Residue: | 303 |
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| Sequence: | MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETDGSIFNESLTANDPDF
LATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGTIEELQNIQQPLLMGTTTH
AARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVLPDVAWHNNIRAELWRKLAVN
CVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIEREGHHTSAEDLRDYVMQVIDATAE
NISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVPENTRLFEMVKRKESEYERIGTGLP
RPW
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| BDBM18137 |
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| n/a |
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| Name | BDBM18137 |
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| Synonyms: | AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,4R,5R)-5-adenin-9-yl-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate;hydrate | adenosine 5 -monophosphate | {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid |
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| Type | Nucleoside or nucleotide |
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| Emp. Form. | C10H14N5O7P |
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| Mol. Mass. | 347.2212 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O |
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| Structure | 
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