Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50195660 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_416468 (CHEMBL907181) |
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Ki | 0.590000±n/a nM |
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Citation | Rennison, D; Moynihan, H; Traynor, JR; Lewis, JW; Husbands, SM Structural determinants of opioid activity in derivatives of 14-aminomorphinones: effects of changes to the chain linking of the C14-amino group to the aryl ring. J Med Chem49:6104-10 (2006) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 11165.58 |
Organism: | GUINEA PIG |
Description: | P97266 |
Residue: | 98 |
Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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BDBM50195660 |
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n/a |
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Name | BDBM50195660 |
Synonyms: | CHEMBL384497 | N-cyclopropylmethyl-14beta-[3'-(4'-chlorophenyl)propylamino]-7,8-dihydronorcodeinone |
Type | Small organic molecule |
Emp. Form. | C30H35ClN2O3 |
Mol. Mass. | 507.064 |
SMILES | COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NCCCc1ccc(Cl)cc1 |
Structure |
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