| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50200174 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_422554 (CHEMBL911053) |
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| Ki | >5000±n/a nM |
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| Citation |  Murineddu, G; Lazzari, P; Ruiu, S; Sanna, A; Loriga, G; Manca, I; Falzoi, M; Dessì, C; Curzu, MM; Chelucci, G; Pani, L; Pinna, GA Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide. J Med Chem49:7502-12 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38220.43 |
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| Organism: | MOUSE |
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| Description: | P47936 |
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| Residue: | 347 |
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| Sequence: | MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILS
SRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLD
VRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYA
LRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
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| BDBM50200174 |
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| n/a |
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| Name | BDBM50200174 |
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| Synonyms: | 1-(2',4'-dichlorophenyl)-6-methyl-N-p-trifluoromethylphenyl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide | CHEMBL219037 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H16Cl2F3N3O |
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| Mol. Mass. | 502.315 |
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| SMILES | Cc1ccc-2c(Cc3c(nn(c-23)-c2ccc(Cl)cc2Cl)C(=O)Nc2ccc(cc2)C(F)(F)F)c1 |
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| Structure | 
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