| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P-selectin glycoprotein ligand 1 |
|---|
| Ligand | BDBM50201904 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_423294 (CHEMBL855465) |
|---|
| IC50 | 1000000±n/a nM |
|---|
| Citation |  Kaila, N; Janz, K; DeBernardo, S; Bedard, PW; Camphausen, RT; Tam, S; Tsao, DH; Keith, JC; Nickerson-Nutter, C; Shilling, A; Young-Sciame, R; Wang, Q Synthesis and biological evaluation of quinoline salicylic acids as P-selectin antagonists. J Med Chem50:21-39 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P-selectin glycoprotein ligand 1 |
|---|
| Name: | P-selectin glycoprotein ligand 1 |
|---|
| Synonyms: | P-selectin glycoprotein ligand 1 | P-selectin/P-selectin glycoprotein ligand 1 | SELPLG | SELPL_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 43174.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_649756 |
|---|
| Residue: | 412 |
|---|
| Sequence: | MPLQLLLLLILLGPGNSLQLWDTWADEAEKALGPLLARDRRQATEYEYLDYDFLPETEPP
EMLRNSTDTTPLTGPGTPESTTVEPAARRSTGLDAGGAVTELTTELANMGNLSTDSAAME
IQTTQPAATEAQTTQPVPTEAQTTPLAATEAQTTRLTATEAQTTPLAATEAQTTPPAATE
AQTTQPTGLEAQTTAPAAMEAQTTAPAAMEAQTTPPAAMEAQTTQTTAMEAQTTAPEATE
AQTTQPTATEAQTTPLAAMEALSTEPSATEALSMEPTTKRGLFIPFSVSSVTHKGIPMAA
SNLSVNYPVGAPDHISVKQCLLAILILALVATIFFVCTVVLAVRLSRKGHMYPVRNYSPT
EMVCISSLLPDGGEGPSATANGGLSKAKSPGLTPEPREDREGDDLTLHSFLP
|
|
|
|---|
| BDBM50201904 |
|---|
| n/a |
|---|
| Name | BDBM50201904 |
|---|
| Synonyms: | 3-hydroxy-2-(4-methoxyphenyl)-7,8-dimethylquinoline-4-carboxylic acid | CHEMBL219646 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H17NO4 |
|---|
| Mol. Mass. | 323.3426 |
|---|
| SMILES | COc1ccc(cc1)-c1nc2c(C)c(C)ccc2c(C(O)=O)c1O |
|---|
| Structure | 
|
|---|
Search and Browse
