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TargetProstaglandin E2 receptor EP2 subtype
LigandBDBM50193931
Substrate/Competitorn/a
Meas. Tech.ChEMBL_424227
Ki 750±n/a nM
Citation Belley MChan CCGareau YGallant MJuteau HHoude KLachance NLabelle MSawyer NTremblay NLamontagne SCarrière MCDenis DGreig GMSlipetz DGordon RChauret NLi CZamboni RJMetters KM Comparison between two classes of selective EP(3) antagonists and their biological activities. Bioorg Med Chem Lett 16:5639-42 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor EP2 subtype
Name:Prostaglandin E2 receptor
Synonyms:PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostanoid EP2 Receptor
Type:Enzyme
Mol. Mass.:39775.71
Organism:Homo sapiens (Human)
Description:P43116
Residue:358
Sequence:
MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50193931
n/a
NameBDBM50193931
Synonyms:3-(2-(4-(benzyloxy)-3-methoxycinnamyl)phenyl)acrylic acid | CHEMBL218626
TypeSmall organic molecule
Emp. Form.C26H24O4
Mol. Mass.400.4664
SMILESCOc1cc(\C=C\Cc2ccccc2\C=C\C(O)=O)ccc1OCc1ccccc1
Structure
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