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TargetProstaglandin E2 receptor EP3 subtype
LigandBDBM50193928
Substrate/Competitorn/a
Meas. Tech.ChEMBL_424228 (CHEMBL909002)
Ki 9±n/a nM
Citation Belley, MChan, CCGareau, YGallant, MJuteau, HHoude, KLachance, NLabelle, MSawyer, NTremblay, NLamontagne, SCarrière, MCDenis, DGreig, GMSlipetz, DGordon, RChauret, NLi, CZamboni, RJMetters, KM Comparison between two classes of selective EP(3) antagonists and their biological activities. Bioorg Med Chem Lett16:5639-42 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor EP3 subtype
Name:Prostaglandin E2 receptor EP3 subtype
Synonyms:PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor
Type:Enzyme
Mol. Mass.:43335.03
Organism:Homo sapiens (Human)
Description:P43115
Residue:390
Sequence:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
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  Blast E-value cutoff:
BDBM50193928
n/a
NameBDBM50193928
Synonyms:3-(2-((E)-3-(2-(benzyloxy)-5-methylphenyl)prop-1-enyl)phenyl)acrylic acid | CHEMBL376053
TypeSmall organic molecule
Emp. Form.C26H24O3
Mol. Mass.384.467
SMILESCc1ccc(OCc2ccccc2)c(C\C=C\c2ccccc2\C=C\C(O)=O)c1
Structure
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