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TargetProstaglandin E2 receptor
LigandBDBM50193930
Substrate/Competitorn/a
Meas. Tech.ChEMBL_424228
Ki 5±n/a nM
Citation Belley MChan CCGareau YGallant MJuteau HHoude KLachance NLabelle MSawyer NTremblay NLamontagne SCarrière MCDenis DGreig GMSlipetz DGordon RChauret NLi CZamboni RJMetters KM Comparison between two classes of selective EP(3) antagonists and their biological activities. Bioorg Med Chem Lett 16:5639-42 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor
Name:Prostaglandin E2 receptor
Synonyms:PGE receptor, EP3 subtype | PGE2-R | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor
Type:Enzyme
Mol. Mass.:43335.03
Organism:Homo sapiens (Human)
Description:P43115
Residue:390
Sequence:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
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  Blast E-value cutoff:
BDBM50193930
n/a
NameBDBM50193930
Synonyms:3-(2-((E)-3-phenylprop-1-enyl)phenyl)-N-(thiophen-2-ylsulfonyl)acrylamide | CHEMBL384878
TypeSmall organic molecule
Emp. Form.C22H19NO3S2
Mol. Mass.409.521
SMILESO=C(NS(=O)(=O)c1cccs1)\C=C\c1ccccc1\C=C\Cc1ccccc1
Structure
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