| Reaction Details |
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 | Report a problem with these data |
| Target | Enoyl-acyl-carrier protein reductase |
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| Ligand | BDBM50070942 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_425612 (CHEMBL910788) |
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| Ki | 79±n/a nM |
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| Citation |  Sharma, SK; Parasuraman, P; Kumar, G; Surolia, N; Surolia, A Green tea catechins potentiate triclosan binding to enoyl-ACP reductase from Plasmodium falciparum (PfENR). J Med Chem50:765-75 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Enoyl-acyl-carrier protein reductase |
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| Name: | Enoyl-acyl-carrier protein reductase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49770.86 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_795989 |
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| Residue: | 432 |
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| Sequence: | MNKISQRLLFLFLHFYTTVCFIQNNTQKTFHNVLQNEQIRGKEKAFYRKEKRENIFIGNK
MKHVHNMNNTHNNNHYMEKEEQDASNINKIKEENKNEDICFIAGIGDTNGYGWGIAKELS
KRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEE
TKNNKRYNMLQNYPIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSK
SSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLG
RNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKN
SASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIM
FLPDDIYRNENE
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| BDBM50070942 |
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| n/a |
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| Name | BDBM50070942 |
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| Synonyms: | (-)-Epigallocatechin gallate | (-)-Epigallocatechin-3-o-gallate | (-)-epigallocatechin 3-gallate | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate | CHEMBL297453 | EGCG | Epigallocatechin 3-gallate | Epigallocatechin monogallate, B | cid_65064 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18O11 |
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| Mol. Mass. | 458.3717 |
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| SMILES | Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c1cc(O)c(O)c(O)c1 |r| |
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| Structure | 
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