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TargetVasopressin receptor
LigandBDBM50205313
Substrate/Competitorn/a
Meas. Tech.ChEMBL_425924
Ki 0.04±n/a nM
Citation Pena AMurat BTrueba MVentura MAWo NCSzeto HHCheng LLStoev SGuillon GManning M Design and synthesis of the first selective agonists for the rat vasopressin V(1b) receptor: based on modifications of deamino-[Cys1]arginine vasopressin at positions 4 and 8. J Med Chem 50:835-47 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Vasopressin receptor
Name:Vasopressin receptor
Synonyms:AVPR1B | VASOPRESSIN V1B | Vasopressin V1b receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:47104.48
Organism:RAT
Description:VASOPRESSIN V1B AVPR1B RAT::P48974
Residue:425
Sequence:
MNSEPSWTATPSPGGTLPVPNATTPWLGRDEELAKVEIGILATVLVLATGGNLAVLLTLG
RHGHKRSRMHLFVLHLALTDLGVALFQVLPQLLWDITYRFQGSDLLCRAVKYLQVLSMFA
STYMLLAMTLDRYLAVCHPLRSLRQPSQSTYPLIAAPWLLAAILSLPQVFIFSLREVIQG
SGVLDCWADFYFSWGPRAYITWTTMAIFVLPVAVLSACYGLICHEIYKNLKVKTQAGREE
RRGWRTWDKSSSSAVATAATRGLPSRVSSISTISRAKIRTVKMTFVIVLAYIACWAPFFS
VQMWSVWDENAPNEDSTNVAFTISMLLGNLSSCCNPWIYMGFNSRLLPRSLSHHACCTGS
KPQVHRQLSTSSLTSRRTTLLTHACGSPTLRLSLNLSLRAKPRPAGSLKDLEQVDGEATM
ETSIF
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  Blast E-value cutoff:
BDBM50205313
n/a
NameBDBM50205313
Synonyms:CHEMBL265859 | d[Leu4]AVP
TypeSmall organic molecule
Emp. Form.C47H67N13O11S2
Mol. Mass.1054.245
SMILES[#6]-[#6](-[#6])-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6](=O)-[#6]-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6]-1=O)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O
Structure
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