| Reaction Details |
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 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
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| Ligand | BDBM50208097 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_429280 (CHEMBL915840) |
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| Ki | >10000±n/a nM |
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| Citation |  Georgsson, J; Sköld, C; Botros, M; Lindeberg, G; Nyberg, F; Karlén, A; Hallberg, A; Larhed, M Synthesis of a new class of druglike angiotensin II C-terminal mimics with affinity for the AT2 receptor. J Med Chem50:1711-5 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-2 angiotensin II receptor |
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| Name: | Type-2 angiotensin II receptor |
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| Synonyms: | AGTR2 | AGTR2_HUMAN | AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41201.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Angiotensin II, central 0 0::P50052 |
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| Residue: | 363 |
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| Sequence: | MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL
VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET
FVS
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| BDBM50208097 |
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| n/a |
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| Name | BDBM50208097 |
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| Synonyms: | (2S,3R)-2-((S)-1-((S)-2-amino-3-(1H-imidazol-5-yl)propanoyl)pyrrolidine-2-carboxamido)-3-methylpentanoic acid | CHEMBL374725 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H27N5O4 |
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| Mol. Mass. | 365.4274 |
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| SMILES | CC[C@@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1cnc[nH]1)C(O)=O |
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| Structure | 
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