| Reaction Details |
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 | Report a problem with these data |
| Target | Creatine kinase M-type |
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| Ligand | BDBM50370908 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_429454 (CHEMBL917153) |
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| Ki | 70000±n/a nM |
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| Citation |  Bretonnet, AS; Jochum, A; Walker, O; Krimm, I; Goekjian, P; Marcillat, O; Lancelin, JM NMR screening applied to the fragment-based generation of inhibitors of creatine kinase exploiting a new interaction proximate to the ATP binding site. J Med Chem50:1865-75 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Creatine kinase M-type |
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| Name: | Creatine kinase M-type |
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| Synonyms: | CKM | Creatine kinase M chain | KCRM_RABIT | M-CK |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43117.10 |
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| Organism: | Oryctolagus cuniculus |
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| Description: | ChEMBL_429452 |
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| Residue: | 381 |
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| Sequence: | MPFGNTHNKYKLNYKSEEEYPDLSKHNNHMAKVLTPDLYKKLRDKETPSGFTLDDVIQTG
VDNPGHPFIMTVGCVAGDEESYTVFKDLFDPIIQDRHGGFKPTDKHKTDLNHENLKGGDD
LDPHYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMT
EQEQQQLIDDHFLFDKPVSPLLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISM
EKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNEHLGYVLTCPSNLGTGLRGGVHVKLA
HLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDISNADRLGSSEVEQVQLVVDGVKLM
VEMEKKLEKGQSIDDMIPAQK
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| BDBM50370908 |
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| n/a |
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| Name | BDBM50370908 |
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| Synonyms: | CHEMBL373782 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H17NO5 |
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| Mol. Mass. | 411.4062 |
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| SMILES | OC(=O)c1ccc(o1)-c1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)c1ccccc1 |
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| Structure | 
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