| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteine protease falcipain-3 [5-492] |
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| Ligand | BDBM50157736 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_430127 (CHEMBL919605) |
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| IC50 | 5800±n/a nM |
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| Citation |  Desai, PV; Patny, A; Sabnis, Y; Tekwani, B; Gut, J; Rosenthal, P; Srivastava, A; Avery, M Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database. J Med Chem47:6609-15 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteine protease falcipain-3 [5-492] |
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| Name: | Cysteine protease falcipain-3 [5-492] |
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| Synonyms: | Cysteine protease falcipain-3 | Q9NAW4_PLAFA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56106.86 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_430127 |
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| Residue: | 488 |
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| Sequence: | MEYSPNEVIKQEREVFVGKEKSGSKFKRKRSIFIVLTVSICFMFALMLFYFTRNENNKTL
FTNSLSNNINDDYIINSLLKSESGKKFIVSKLEELISSYDKEKKMRTTGAEENNMNMNGI
DDKDNKSVSFVNKKNGNLKVNNNNQVSYSNLFDTKFLMDNLETVNLFYIFLKENNKKYET
SEEMQKRFIIFSENYRKIELHNKKTNSLYKRGMNKFGDLSPEEFRSKYLNLKTHGPFKTL
SPPVSYEANYEDVIKKYKPADAKLDRIAYDWRLHGGVTPVKDQALCGSCWAFSSVGSVES
QYAIRKKALFLFSEQELVDCSVKNNGCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPET
CNLKRCNERYTIKSYVSIPDDKFKEALRYLGPISISIAASDDFAFYRGGFYDGECGAAPN
HAVILVGYGMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGT
EAYVPLLE
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| BDBM50157736 |
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| n/a |
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| Name | BDBM50157736 |
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| Synonyms: | 3-((5-(2,3-dihydroxybenzylideneamino)naphthalen-1-ylimino)methyl)benzene-1,2-diol | CHEMBL222325 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H18N2O4 |
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| Mol. Mass. | 398.4107 |
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| SMILES | Oc1cccc(\C=N\c2cccc3c(cccc23)\N=C/c2cccc(O)c2O)c1O |
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| Structure | 
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