| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Enoyl-acyl-carrier protein reductase |
|---|
| Ligand | BDBM50211890 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_436470 (CHEMBL904775) |
|---|
| Ki | 7300±n/a nM |
|---|
| Citation |  Kumar, G; Parasuraman, P; Sharma, SK; Banerjee, T; Karmodiya, K; Surolia, N; Surolia, A Discovery of a rhodanine class of compounds as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase. J Med Chem50:2665-75 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Enoyl-acyl-carrier protein reductase |
|---|
| Name: | Enoyl-acyl-carrier protein reductase |
|---|
| Synonyms: | n/a |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49770.86 |
|---|
| Organism: | Plasmodium falciparum |
|---|
| Description: | ChEMBL_795989 |
|---|
| Residue: | 432 |
|---|
| Sequence: | MNKISQRLLFLFLHFYTTVCFIQNNTQKTFHNVLQNEQIRGKEKAFYRKEKRENIFIGNK
MKHVHNMNNTHNNNHYMEKEEQDASNINKIKEENKNEDICFIAGIGDTNGYGWGIAKELS
KRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEE
TKNNKRYNMLQNYPIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSK
SSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLG
RNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKN
SASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIM
FLPDDIYRNENE
|
|
|
|---|
| BDBM50211890 |
|---|
| n/a |
|---|
| Name | BDBM50211890 |
|---|
| Synonyms: | 6-(5-(4-(hexyloxy)-3-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoic acid | CHEMBL227647 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H31NO5S2 |
|---|
| Mol. Mass. | 465.626 |
|---|
| SMILES | CCCCCCOc1ccc(\C=C2/SC(=S)N(CCCCCC(O)=O)C2=O)cc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
