| Reaction Details |
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 | Report a problem with these data |
| Target | Enoyl-acyl-carrier protein reductase |
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| Ligand | BDBM50211907 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_436470 (CHEMBL904775) |
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| Ki | 560±n/a nM |
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| Citation |  Kumar, G; Parasuraman, P; Sharma, SK; Banerjee, T; Karmodiya, K; Surolia, N; Surolia, A Discovery of a rhodanine class of compounds as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase. J Med Chem50:2665-75 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Enoyl-acyl-carrier protein reductase |
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| Name: | Enoyl-acyl-carrier protein reductase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49770.86 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_795989 |
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| Residue: | 432 |
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| Sequence: | MNKISQRLLFLFLHFYTTVCFIQNNTQKTFHNVLQNEQIRGKEKAFYRKEKRENIFIGNK
MKHVHNMNNTHNNNHYMEKEEQDASNINKIKEENKNEDICFIAGIGDTNGYGWGIAKELS
KRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEE
TKNNKRYNMLQNYPIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSK
SSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLG
RNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKN
SASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIM
FLPDDIYRNENE
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| BDBM50211907 |
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| n/a |
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| Name | BDBM50211907 |
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| Synonyms: | 5-((5-(2,3-dichlorophenyl)furan-2-yl)methylene)-2-thioxothiazolidin-4-one | CHEMBL227563 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H7Cl2NO2S2 |
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| Mol. Mass. | 356.247 |
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| SMILES | SC1=NC(=O)C(S1)=Cc1ccc(o1)-c1cccc(Cl)c1Cl |w:7.8,t:1| |
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| Structure | 
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