| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50027233 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_439881 (CHEMBL890202) |
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| Ki | >10000±n/a nM |
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| Citation |  Simpson, DS; Katavic, PL; Lozama, A; Harding, WW; Parrish, D; Deschamps, JR; Dersch, CM; Partilla, JS; Rothman, RB; Navarro, H; Prisinzano, TE Synthetic studies of neoclerodane diterpenes from Salvia divinorum: preparation and opioid receptor activity of salvinicin analogues. J Med Chem50:3596-603 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50027233 |
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| n/a |
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| Name | BDBM50027233 |
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| Synonyms: | Salvinicin B |
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| Type | Small organic molecule |
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| Emp. Form. | C26H38O11 |
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| Mol. Mass. | 526.5733 |
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| SMILES | [H][C@@]1(CC(=O)[C@]2([H])CC[C@@]3(C)[C@@H](C[C@H](OC(C)=O)C(=O)[C@]3([H])[C@@]2(C)C1)C(=O)OC)[C@@]1(O)[C@H](O)[C@H](OC)O[C@@H]1OC |r| |
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| Structure | 
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