| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50216145 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_439882 (CHEMBL890203) |
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| Ki | >10000±n/a nM |
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| Citation |  Simpson, DS; Katavic, PL; Lozama, A; Harding, WW; Parrish, D; Deschamps, JR; Dersch, CM; Partilla, JS; Rothman, RB; Navarro, H; Prisinzano, TE Synthetic studies of neoclerodane diterpenes from Salvia divinorum: preparation and opioid receptor activity of salvinicin analogues. J Med Chem50:3596-603 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50216145 |
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| n/a |
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| Name | BDBM50216145 |
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| Synonyms: | CHEMBL226727 | methyl (1S,2R,7R,10R,11R,13S)-13-(acetyloxy)-4-[(2S,3R,4S,5R)-4-(acetyloxy)-3-hydroxy-2,5-dimethoxyoxolan-3-yl]-2,10-dimethyl-6,14-dioxo-5-oxatricyclo[8.4.0.0^{2,7}]tetradecane-11-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C27H38O13 |
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| Mol. Mass. | 570.5828 |
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| SMILES | CO[C@@H]1O[C@H](OC)[C@](O)([C@@H]1OC(C)=O)C1C[C@@]2(C)[C@@H](CC[C@@]3(C)[C@@H](C[C@H](OC(C)=O)C(=O)[C@H]23)C(=O)OC)C(=O)O1 |
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| Structure | 
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