| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 3 |
|---|
| Ligand | BDBM50221406 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_449604 (CHEMBL898699) |
|---|
| Ki | 2300±n/a nM |
|---|
| Citation |  Nishimori, I; Minakuchi, T; Onishi, S; Vullo, D; Cecchi, A; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides. Bioorg Med Chem15:7229-36 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 3 |
|---|
| Name: | Carbonic anhydrase 3 |
|---|
| Synonyms: | CA-III | CA3 | CAH3_HUMAN | Carbonate dehydratase III | Carbonic Anhydrase III | Carbonic anhydrase | Carbonic anhydrase 3 (CA III) | Carbonic anhydrase III (CA III) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29562.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human cloned isozyme. |
|---|
| Residue: | 260 |
|---|
| Sequence: | MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTIL
NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL
VHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDP
SCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPL
VSNWRPPQPINNRVVRASFK
|
|
|
|---|
| BDBM50221406 |
|---|
| n/a |
|---|
| Name | BDBM50221406 |
|---|
| Synonyms: | 6-acetamido-4-hydroxy-3-((4-sulfamoylphenyl)diazenyl)naphthalene-2,7-disulfonic acid | 6-acetylamino-4-hydroxy-3-(4-sulfamoyl-phenylazo)-naphthalene-2,7-disulfonic acid | CHEMBL237251 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H16N4O10S3 |
|---|
| Mol. Mass. | 544.535 |
|---|
| SMILES | CC(=O)Nc1cc2c(O)c(N=Nc3ccc(cc3)S(N)(=O)=O)c(cc2cc1S(O)(=O)=O)S(O)(=O)=O |w:10.9| |
|---|
| Structure | 
|
|---|
Search and Browse
