| Reaction Details |
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 | Report a problem with these data |
| Target | Dipeptidyl peptidase 4 |
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| Ligand | BDBM50206820 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_454770 (CHEMBL886798) |
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| Ki | 56.2±n/a nM |
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| Citation |  Ahn, JH; Shin, MS; Jun, MA; Jung, SH; Kang, SK; Kim, KR; Rhee, SD; Kang, NS; Kim, SY; Sohn, SK; Kim, SG; Jin, MS; Lee, JO; Cheon, HG; Kim, SS Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors. Bioorg Med Chem Lett17:2622-8 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dipeptidyl peptidase 4 |
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| Name: | Dipeptidyl peptidase 4 |
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| Synonyms: | CD26 | CD_antigen=CD26 | DPP IV | DPP4 | DPP4_PIG | Dipeptidyl peptidase 4 | Dipeptidyl peptidase 4 membrane form | Dipeptidyl peptidase 4 soluble form | Dipeptidyl peptidase IV | Dipeptidyl peptidase IV membrane form | Dipeptidyl peptidase IV soluble form | T-cell activation antigen CD26 |
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| Type: | Enzyme |
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| Mol. Mass.: | 88235.21 |
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| Organism: | Sus scrofa (pig) |
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| Description: | n/a |
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| Residue: | 766 |
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| Sequence: | MKTPWKVLLGLLGIAALVTVITVPVVLLNKGTDDAAADSRRTYTLTDYLKSTFRVKFYTL
QWISDHEYLYKQENNILLFNAEYGNSSIFLENSTFDELGYSTNDYSVSPDRQFILFEYNY
VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWITWSPVGHKLAYVWNNDIYVKNEPNL
SSQRITWTGKENVIYNGVTDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF
YSDESLQYPKTVRIPYPKAGAENPTVKFFVVDTRTLSPNASVTSYQIVPPASVLIGDHYL
CGVTWVTEERISLQWIRRAQNYSIIDICDYDESTGRWISSVARQHIEISTTGWVGRFRPA
EPHFTSDGNSFYKIISNEEGYKHICHFQTDKSNCTFITKGAWEVIGIEALTSDYLYYISN
EHKGMPGGRNLYRIQLNDYTKVTCLSCELNPERCQYYSASFSNKAKYYQLRCFGPGLPLY
TLHSSSSDKELRVLEDNSALDKMLQDVQMPSKKLDVINLHGTKFWYQMILPPHFDKSKKY
PLLIEVYAGPCSQKVDTVFRLSWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGT
FEVEDQIEATRQFSKMGFVDDKRIAIWGWSYGGYVTSMVLGAGSGVFKCGIAVAPVSKWE
YYDSVYTERYMGLPTPEDNLDYYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQLS
KALVDAGVDFQTMWYTDEDHGIASNMAHQHIYTHMSHFLKQCFSLP
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| BDBM50206820 |
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| n/a |
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| Name | BDBM50206820 |
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| Synonyms: | (R)-3-amino-1-(2-benzoyl-1,2-diazepan-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride | CHEMBL539611 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24F3N3O2 |
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| Mol. Mass. | 419.4401 |
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| SMILES | N[C@@H](CC(=O)N1CCCCCN1C(=O)c1ccccc1)Cc1cc(F)c(F)cc1F |
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| Structure | 
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