| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
|---|
| Ligand | BDBM50222838 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_458048 (CHEMBL925386) |
|---|
| IC50 | 110±n/a nM |
|---|
| Citation |  Ohta, H; Ishizaka, T; Tatsuzuki, M; Yoshinaga, M; Iida, I; Tomishima, Y; Toda, Y; Saito, S N-Alkylidenearylcarboxamides as new potent and selective CB(2) cannabinoid receptor agonists with good oral bioavailability. Bioorg Med Chem Lett17:6299-304 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 2 |
|---|
| Name: | Cannabinoid receptor 2 |
|---|
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 39690.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P34972 |
|---|
| Residue: | 360 |
|---|
| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
|
|
|
|---|
| BDBM50222838 |
|---|
| n/a |
|---|
| Name | BDBM50222838 |
|---|
| Synonyms: | CHEMBL248201 | ethyl 3-(cyclopropylmethyl)-4-methyl-2-(3-(trifluoromethyl)benzamido)-2,3-dihydrothiazole-5-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H19F3N2O3S |
|---|
| Mol. Mass. | 412.426 |
|---|
| SMILES | CCOC(=O)c1s\c(=N/C(=O)c2cccc(c2)C(F)(F)F)n(CC2CC2)c1C |
|---|
| Structure | 
|
|---|
Search and Browse
