| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50225148 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_458569 (CHEMBL941882) |
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| Ki | 290±n/a nM |
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| Citation |  Manera, C; Cascio, MG; Benetti, V; Allarà, M; Tuccinardi, T; Martinelli, A; Saccomanni, G; Vivoli, E; Ghelardini, C; Di Marzo, V; Ferrarini, PL New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists. Bioorg Med Chem Lett17:6505-10 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50225148 |
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| n/a |
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| Name | BDBM50225148 |
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| Synonyms: | CHEMBL250769 | N-cycloheptyl-1-(2-morpholinoethyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C23H31N3O3 |
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| Mol. Mass. | 397.5105 |
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| SMILES | O=C(NC1CCCCCC1)c1cn(CCN2CCOCC2)c2ccccc2c1=O |
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| Structure | 
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