| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM50211826 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_459050 (CHEMBL925142) |
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| Ki | 100±n/a nM |
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| Citation |  Supuran, CT; Scozzafava, A Carbonic anhydrases as targets for medicinal chemistry. Bioorg Med Chem15:4336-50 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM50211826 |
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| n/a |
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| Name | BDBM50211826 |
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| Synonyms: | 2-[(1E)-{[2-(4-sulfamoylphenyl)ethyl]imino}methyl]phenyl N-[(4-chlorobenzene)sulfonyl]carbamate | CHEMBL399457 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20ClN3O6S2 |
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| Mol. Mass. | 521.994 |
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| SMILES | NS(=O)(=O)c1ccc(CCN=Cc2ccccc2OC(=O)NS(=O)(=O)c2ccc(Cl)cc2)cc1 |w:11.11| |
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| Structure | 
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