| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
|---|
| Ligand | BDBM10826 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_462121 (CHEMBL945895) |
|---|
| IC50 | 1500±n/a nM |
|---|
| Citation |  Cavalli, A; Bolognesi, ML; Minarini, A; Rosini, M; Tumiatti, V; Recanatini, M; Melchiorre, C Multi-target-directed ligands to combat neurodegenerative diseases. J Med Chem51:347-72 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] B |
|---|
| Name: | Amine oxidase [flavin-containing] B |
|---|
| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 58768.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P27338 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
|
|
|
|---|
| BDBM10826 |
|---|
| n/a |
|---|
| Name | BDBM10826 |
|---|
| Synonyms: | 3-{2-[methyl(prop-2-yn-1-yl)amino]propyl}phenyl N-hexyl-N-methylcarbamate | CHEMBL356385 | Phenethylamine deriv. 53d |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H32N2O2 |
|---|
| Mol. Mass. | 344.491 |
|---|
| SMILES | CCCCCCN(C)C(=O)Oc1cccc(CC(C)N(C)CC#C)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
