| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
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| Ligand | BDBM50231957 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_462120 (CHEMBL945894) |
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| IC50 | 1120±n/a nM |
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| Citation |  Cavalli, A; Bolognesi, ML; Minarini, A; Rosini, M; Tumiatti, V; Recanatini, M; Melchiorre, C Multi-target-directed ligands to combat neurodegenerative diseases. J Med Chem51:347-72 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] A |
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| Name: | Amine oxidase [flavin-containing] A |
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| Synonyms: | AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) |
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| Type: | Protein |
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| Mol. Mass.: | 59689.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21397 |
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| Residue: | 527 |
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| Sequence: | MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
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| BDBM50231957 |
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| n/a |
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| Name | BDBM50231957 |
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| Synonyms: | 7-(3-Chloro-benzyloxy)-3,4-dimethyl-chromen-2-one | 7-(3-chlorobenzyloxy)-3,4-dimethyl-2H-chromen-2-one | CHEMBL109018 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15ClO3 |
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| Mol. Mass. | 314.763 |
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| SMILES | Cc1c(C)c(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 |
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| Structure | 
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