| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50233724 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_462436 (CHEMBL927252) |
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| Ki | 1.3±n/a nM |
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| Citation |  Krueger, AC; Xu, Y; Kati, WM; Kempf, DJ; Maring, CJ; McDaniel, KF; Molla, A; Montgomery, D; Kohlbrenner, WE Synthesis of potent pyrrolidine influenza neuraminidase inhibitors. Bioorg Med Chem Lett18:1692-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | Influenza B Virus Neuraminidase | NA | NRAM_INBLE | Neuraminidase | Neuraminidase B |
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| Type: | Enzyme |
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| Mol. Mass.: | 51446.67 |
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| Organism: | Influenza B virus (B/Lee/40) |
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| Description: | n/a |
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| Residue: | 466 |
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| Sequence: | MLPSTVQTLTLLLTSGGVLLSLYVSASLSYLLYSDVLLKFSSTKTTAPTMSLECTNASNA
QTVNHSATKEMTFPPPEPEWTYPRLSCQGSTFQKALLISPHRFGEIKGNSAPLIIREPFV
ACGPKECRHFALTHYAAQPGGYYNGTRKDRNKLRHLVSVKLGKIPTVENSIFHMAAWSGS
ACHDGREWTYIGVDGPDNDALVKIKYGEAYTDTYHSYAHNILRTQESACNCIGGDCYLMI
TDGSASGISKCRFLKIREGRIIKEILPTGRVEHTEECTCGFASNKTIECACRDNSYTAKR
PFVKLNVETDTAEIRLMCTKTYLDTPRPDDGSIAGPCESNGDKWLGGIKGGFVHQRMASK
IGRWYSRTMSKTNRMGMELYVKYDGDPWTDSDALTLSGVMVSIEEPGWYSFGFEIKDKKC
DVPCIGIEMVHDGGKDTWHSAATAIYCLMGSGQLLWDTVTGVDMAL
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| BDBM50233724 |
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| n/a |
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| Name | BDBM50233724 |
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| Synonyms: | (2R,4S,5R)-5-((1R,2S)-1-acetamido-2-hydroxypentyl)-4-(prop-1-enyl)pyrrolidine-2-carboxylic acid | CHEMBL253410 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H26N2O4 |
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| Mol. Mass. | 298.3779 |
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| SMILES | CCC[C@H](O)[C@H](NC(C)=O)[C@@H]1N[C@H](C[C@H]1\C=C/C)C(O)=O |
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| Structure | 
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