| Reaction Details |
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 | Report a problem with these data |
| Target | Intermediate conductance calcium-activated potassium channel protein 4 |
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| Ligand | BDBM50371393 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_463302 (CHEMBL948111) |
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| IC50 | >10000±n/a nM |
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| Citation |  McNaughton-Smith, GA; Burns, JF; Stocker, JW; Rigdon, GC; Creech, C; Arrington, S; Shelton, T; de Franceschi, L Novel inhibitors of the Gardos channel for the treatment of sickle cell disease. J Med Chem51:976-82 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Intermediate conductance calcium-activated potassium channel protein 4 |
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| Name: | Intermediate conductance calcium-activated potassium channel protein 4 |
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| Synonyms: | IK1 | IKCA1 | KCA4 | KCNN4 | KCNN4_HUMAN | Putative Gardos channel | SK4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47723.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1361891 |
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| Residue: | 427 |
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| Sequence: | MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFL
VKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPA
PVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYR
SIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDT
LWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHN
FMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRK
LREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLP
EPSQQSK
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| BDBM50371393 |
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| n/a |
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| Name | BDBM50371393 |
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| Synonyms: | 2,2,2-triphenylacetic acid | CHEMBL271207 | J-640276 | Triphenylacetic Acid |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16O2 |
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| Mol. Mass. | 288.3398 |
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| SMILES | OC(=O)C(c1ccccc1)(c1ccccc1)c1ccccc1 |
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| Structure | 
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