| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
|---|
| Ligand | BDBM50371465 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_463656 (CHEMBL930824) |
|---|
| Ki | 15.3±n/a nM |
|---|
| Citation |  Peters, JU; Lübbers, T; Alanine, A; Kolczewski, S; Blasco, F; Steward, L Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation. Bioorg Med Chem Lett18:256-61 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 7 |
|---|
| Name: | 5-hydroxytryptamine receptor 7 |
|---|
| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 53573.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P34969 |
|---|
| Residue: | 479 |
|---|
| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
|
|
|
|---|
| BDBM50371465 |
|---|
| n/a |
|---|
| Name | BDBM50371465 |
|---|
| Synonyms: | CHEMBL269964 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H12ClN3 |
|---|
| Mol. Mass. | 209.675 |
|---|
| SMILES | CNC1=Nc2cccc(Cl)c2C(C)N1 |t:2| |
|---|
| Structure | 
|
|---|
Search and Browse
