| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 8 |
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| Ligand | BDBM50372437 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_464936 (CHEMBL946993) |
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| IC50 | >10000±n/a nM |
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| Citation |  Paris, M; Porcelloni, M; Binaschi, M; Fattori, D Histone deacetylase inhibitors: from bench to clinic. J Med Chem51:1505-29 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 8 |
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| Name: | Histone deacetylase 8 |
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| Synonyms: | HD8 | HDAC8 | HDAC8_HUMAN | HDACL1 | Histone deacetylase 8 (HDAC-8) | Human HDAC8 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41749.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9BY41 |
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| Residue: | 377 |
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| Sequence: | MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH
RIQQILNYIKGNLKHVV
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| BDBM50372437 |
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| n/a |
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| Name | BDBM50372437 |
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| Synonyms: | CHEMBL552879 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H20N2O2S |
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| Mol. Mass. | 280.386 |
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| SMILES | ONC(=S)CCCCCCC(=O)Nc1ccccc1 |
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| Structure | 
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