| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 6-phosphogluconate dehydrogenase, decarboxylating |
|---|
| Ligand | BDBM23417 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_467396 (CHEMBL921930) |
|---|
| IC50 | >1000000±n/a nM |
|---|
| Citation |  Shin, ES; Park, J; Shin, JM; Cho, D; Cho, SY; Shin, DW; Ham, M; Kim, JB; Lee, TR Catechin gallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme. Bioorg Med Chem16:3580-6 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 6-phosphogluconate dehydrogenase, decarboxylating |
|---|
| Name: | 6-phosphogluconate dehydrogenase, decarboxylating |
|---|
| Synonyms: | 6-phosphogluconate dehydrogenase | 6-phosphogluconate dehydrogenase (6PGD) | 6PGD_HUMAN | PGD | PGDH |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 53143.42 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P52209 |
|---|
| Residue: | 483 |
|---|
| Sequence: | MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE
MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG
ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG
HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL
KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA
SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL
MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM
PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS
YNA
|
|
|
|---|
| BDBM23417 |
|---|
| n/a |
|---|
| Name | BDBM23417 |
|---|
| Synonyms: | α-CA inhibitor, 4 | (-)-Epicatechin | (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol | Epicatechin | L-Epicatechin | cid_72276 |
|---|
| Type | Flavonol |
|---|
| Emp. Form. | C15H14O6 |
|---|
| Mol. Mass. | 290.2681 |
|---|
| SMILES | O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
