| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
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| Ligand | BDBM50373654 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_468024 (CHEMBL948247) |
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| Ki | 3.4±n/a nM |
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| Citation |  Li, G; Stamford, AW; Huang, Y; Cheng, KC; Cook, J; Farley, C; Gao, J; Ghibaudi, L; Greenlee, WJ; Guzzi, M; van Heek, M; Hwa, JJ; Kelly, J; Mullins, D; Parker, EM; Wainhaus, S; Zhang, X Discovery of novel orally active ureido NPY Y5 receptor antagonists. Bioorg Med Chem Lett18:1146-50 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 5 |
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| Name: | Neuropeptide Y receptor type 5 |
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| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 50746.64 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15761 |
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| Residue: | 445 |
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| Sequence: | MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL
LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP
ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK
KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL
NPILYGFLNNGIKADLVSLIHCLHM
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| BDBM50373654 |
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| n/a |
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| Name | BDBM50373654 |
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| Synonyms: | CHEMBL257708 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H32F2N4O3S |
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| Mol. Mass. | 458.566 |
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| SMILES | CCCS(=O)(=O)N1CCC(CC1)N(C)C(=O)NC1CCN(CC1)c1cc(F)cc(F)c1 |
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| Structure | 
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