| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
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| Ligand | BDBM50373818 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_468544 (CHEMBL930969) |
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| IC50 | 50±n/a nM |
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| Citation |  Beck, HP; Kohn, T; Rubenstein, S; Hedberg, C; Schwandner, R; Hasslinger, K; Dai, K; Li, C; Liang, L; Wesche, H; Frank, B; An, S; Wickramasinghe, D; Jaen, J; Medina, J; Hungate, R; Shen, W Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents. Bioorg Med Chem Lett18:1037-41 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 1 |
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| Name: | Lysophosphatidic acid receptor 1 |
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| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41120.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92633 |
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| Residue: | 364 |
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| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
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| BDBM50373818 |
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| n/a |
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| Name | BDBM50373818 |
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| Synonyms: | CHEMBL404575 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18N2O3 |
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| Mol. Mass. | 322.3578 |
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| SMILES | CC(OC(=O)Nc1c(C)noc1-c1ccccc1)c1ccccc1 |
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| Structure | 
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