| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 2 |
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| Ligand | BDBM50373817 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_468543 (CHEMBL930968) |
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| IC50 | 260±n/a nM |
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| Citation |  Beck, HP; Kohn, T; Rubenstein, S; Hedberg, C; Schwandner, R; Hasslinger, K; Dai, K; Li, C; Liang, L; Wesche, H; Frank, B; An, S; Wickramasinghe, D; Jaen, J; Medina, J; Hungate, R; Shen, W Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents. Bioorg Med Chem Lett18:1037-41 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 2 |
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| Name: | Lysophosphatidic acid receptor 2 |
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| Synonyms: | EDG4 | LPA receptor 2 | LPA-2 | LPA2 | LPAR2 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 | Lysophosphatidic acid receptor Edg-4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39103.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1451385 |
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| Residue: | 351 |
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| Sequence: | MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASN
RRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVA
TLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSR
MAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLV
KTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA
EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
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| BDBM50373817 |
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| n/a |
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| Name | BDBM50373817 |
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| Synonyms: | CHEMBL404452 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27N5S |
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| Mol. Mass. | 381.538 |
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| SMILES | C[C@@H](CN1CCN(CC1)c1ccccc1C)Nc1ncnc2c(C)csc12 |
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| Structure | 
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