| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 3 |
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| Ligand | BDBM50373818 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_468545 (CHEMBL931968) |
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| IC50 | 12000±n/a nM |
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| Citation |  Beck, HP; Kohn, T; Rubenstein, S; Hedberg, C; Schwandner, R; Hasslinger, K; Dai, K; Li, C; Liang, L; Wesche, H; Frank, B; An, S; Wickramasinghe, D; Jaen, J; Medina, J; Hungate, R; Shen, W Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents. Bioorg Med Chem Lett18:1037-41 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 3 |
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| Name: | Lysophosphatidic acid receptor 3 |
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| Synonyms: | EDG7 | LPA3 | LPAR3 | LPAR3_HUMAN | Lysophosphatidic acid receptor 1/3 | Lysophosphatidic acid receptor 3 (LPAR3) | Lysophosphatidic acid receptor Edg-7 |
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| Type: | Enzyme |
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| Mol. Mass.: | 40149.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9UBY5 |
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| Residue: | 353 |
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| Sequence: | MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK
FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL
LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA
PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT
VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM
YGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
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| BDBM50373818 |
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| n/a |
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| Name | BDBM50373818 |
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| Synonyms: | CHEMBL404575 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18N2O3 |
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| Mol. Mass. | 322.3578 |
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| SMILES | CC(OC(=O)Nc1c(C)noc1-c1ccccc1)c1ccccc1 |
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| Structure | 
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