| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
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| Ligand | BDBM50373942 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_468778 (CHEMBL931918) |
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| EC50 | 434±n/a nM |
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| Citation |  Xiao, Y; Araldi, GL; Zhao, Z; Reddy, A; Karra, S; Brugger, N; Fischer, D; Palmer, E; Bao, B; McKenna, SD Synthesis and evaluation of a gamma-lactam as a highly selective EP2 and EP4 receptor agonist. Bioorg Med Chem Lett18:821-4 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP2 subtype |
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| Name: | Prostaglandin E2 receptor EP2 subtype |
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| Synonyms: | PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 39775.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43116 |
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| Residue: | 358 |
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| Sequence: | MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
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| BDBM50373942 |
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| n/a |
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| Name | BDBM50373942 |
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| Synonyms: | CHEMBL272276 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25NO4 |
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| Mol. Mass. | 379.4489 |
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| SMILES | O[C@@H](Cc1ccccc1)\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O |
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| Structure | 
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