| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein kinase C gamma type |
|---|
| Ligand | BDBM50374190 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_469037 (CHEMBL930946) |
|---|
| Ki | 61±n/a nM |
|---|
| Citation |  Sugimoto, T; Itagaki, K; Irie, K Design and physicochemical properties of new fluorescent ligands of protein kinase C isozymes focused on CH/pi interaction. Bioorg Med Chem16:650-7 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein kinase C gamma type |
|---|
| Name: | Protein kinase C gamma type |
|---|
| Synonyms: | KPCG_HUMAN | PKC gamma | PKC-gamma | PKCG | PRKCG | Protein kinase C gamma | Protein kinase C gamma type | Protein kinase C, PKC; classical/novel | Protein kinase C, gamma |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 78458.05 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | The recombinant human PKC enzymes were
produced using a baculovirus expression system in SF9 cells
|
|---|
| Residue: | 697 |
|---|
| Sequence: | MAGLGPGVGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG
KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL
LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTADEIHVTVGEA
RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRL
SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ
KFEACNYPLELYERVRMGPSSSPIPSPSPSPTDPKRCFFGASPGRLHISDFSFLMVLGKG
SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL
HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD
LKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS
FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGS
GPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL
VLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM
|
|
|
|---|
| BDBM50374190 |
|---|
| n/a |
|---|
| Name | BDBM50374190 |
|---|
| Synonyms: | CHEMBL271403 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H22N4O2 |
|---|
| Mol. Mass. | 326.3929 |
|---|
| SMILES | CC(C)[C@@H]1N(C)c2ccc3cnn4cc(C[C@@H](CO)NC1=O)c2c34 |
|---|
| Structure | 
|
|---|
Search and Browse
