| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 [30-579] |
|---|
| Ligand | BDBM50161512 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_469283 (CHEMBL949127) |
|---|
| Ki | 0.29±n/a nM |
|---|
| Citation |  Maryanoff, BE; Costanzo, MJ Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality. Bioorg Med Chem16:1562-95 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Fatty-acid amide hydrolase 1 [30-579] |
|---|
| Name: | Fatty-acid amide hydrolase 1 [30-579] |
|---|
| Synonyms: | Anandamide amidohydrolase 1 | FAAH1_RAT | Faah | Faah1 | Fatty Acid Amide Hydrolase | Fatty Acid Amide Hydrolic, FAAH | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Fatty-acid amide hydrolase 1 (FAAH) | Fatty-acid amide hydrolase 1 (aa 30-579) | Oleamide hydrolase 1 |
|---|
| Type: | Single-pass membrane protein; homodimer |
|---|
| Mol. Mass.: | 60474.00 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P97612 (aa 30-579) |
|---|
| Residue: | 550 |
|---|
| Sequence: | RWTGRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSG
ELSPEAVFFTYLGKAWEVNKGTNCVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKG
HDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMLSFDCSNPLFGQTMNPWK
SSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGC
VYGQTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGY
YETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNIPYALEVLSAGGLFSDGGRSFL
QNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAFLNSMRPRSAEKLWKLQH
EIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAISYTVLYNCLDFPAGVVPV
TTVTAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVE
QLMTPQKQPS
|
|
|
|---|
| BDBM50161512 |
|---|
| n/a |
|---|
| Name | BDBM50161512 |
|---|
| Synonyms: | 7-Phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)-heptan-1-one | 7-Phenyl-1-(5-pyridin-2-yl-[1,3,4]oxadiazol-2-yl)-heptan-1-one | 7-phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)heptan-1-one | CHEMBL178398 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H21N3O2 |
|---|
| Mol. Mass. | 335.3996 |
|---|
| SMILES | O=C(CCCCCCc1ccccc1)c1nnc(o1)-c1ccccn1 |
|---|
| Structure | 
|
|---|
Search and Browse
