| Reaction Details |
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 | Report a problem with these data |
| Target | Granzyme B |
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| Ligand | BDBM50374384 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_469245 (CHEMBL948945) |
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| Ki | 7±n/a nM |
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| Citation |  Maryanoff, BE; Costanzo, MJ Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality. Bioorg Med Chem16:1562-95 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Granzyme B |
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| Name: | Granzyme B |
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| Synonyms: | CGL1 | CSPB | CTLA1 | GRAB_HUMAN | GRB | GZMB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27735.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_469245 |
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| Residue: | 247 |
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| Sequence: | MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVL
TAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKR
TRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY
YDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWI
KKTMKRY
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| BDBM50374384 |
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| n/a |
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| Name | BDBM50374384 |
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| Synonyms: | CHEMBL255387 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H36N6O8 |
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| Mol. Mass. | 644.6743 |
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| SMILES | CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@H]1CCc2cccc3C[C@H](N(c23)C1=O)C(=O)N[C@@H](CC(O)=O)C(=O)c1nnc(o1)-c1ccccc1 |
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| Structure | 
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