| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 12 |
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| Ligand | BDBM50374555 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_469575 (CHEMBL933022) |
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| IC50 | 16±n/a nM |
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| Citation |  Douglass, JG; deCamp, JB; Fulcher, EH; Jones, W; Mahanty, S; Morgan, A; Smirnov, D; Boyer, JL; Watson, PS Adenosine analogues as inhibitors of P2Y12 receptor mediated platelet aggregation. Bioorg Med Chem Lett18:2167-71 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 12 |
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| Name: | P2Y purinoceptor 12 |
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| Synonyms: | ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39458.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H244 |
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| Residue: | 342 |
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| Sequence: | MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI
IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI
DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS
EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI
IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF
LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
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| BDBM50374555 |
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| n/a |
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| Name | BDBM50374555 |
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| Synonyms: | REGRELOR DISODIUM |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23N6O8P |
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| Mol. Mass. | 530.4283 |
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| SMILES | CCNC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])([O-])=O)[C@H]2O[C@@H](O[C@@H]12)\C=C\c1ccccc1 |
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| Structure | 
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