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TargetMu-type opioid receptor
LigandBDBM50375377
Substrate/Competitorn/a
Meas. Tech.ChEMBL_471597
Ki 5700±n/a nM
Citation Jung BEnglberger WFröhlich RSchepmann DLehmkuhl KWünsch B Synthesis and pharmacological evaluation of bicyclic SNC80 analogues with separated benzhydryl moiety. Bioorg Med Chem 16:2870-85 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50375377
n/a
NameBDBM50375377
Synonyms:CHEMBL409266
TypeSmall organic molecule
Emp. Form.C28H39N3O
Mol. Mass.433.6288
SMILESCCCN1C[C@@H]2[C@@H](CC[C@H]1CN2Cc1ccc(cc1)C(=O)N(CC)CC)c1ccccc1 |TLB:2:3:10.11:8.7.6,THB:26:6:3.4:10.11,12:11:3.4:8.7.6|
Structure
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