| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50003222 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_471789 (CHEMBL939997) |
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| Ki | 3.6±n/a nM |
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| Citation |  Stefanachi, A; Brea, JM; Cadavid, MI; Centeno, NB; Esteve, C; Loza, MI; Martinez, A; Nieto, R; Raviña, E; Sanz, F; Segarra, V; Sotelo, E; Vidal, B; Carotti, A 1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor. Bioorg Med Chem16:2852-69 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50003222 |
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| n/a |
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| Name | BDBM50003222 |
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| Synonyms: | CHEMBL440418 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H25ClN6O4S |
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| Mol. Mass. | 565.043 |
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| SMILES | Cn1c2cc([nH]c2c(=O)n(C)c1=O)-c1ccc(OCC(=O)N2CCN(CC2)c2nc3cc(Cl)ccc3s2)cc1 |
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| Structure | 
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