| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Casein kinase I isoform alpha |
|---|
| Ligand | BDBM15211 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_473616 (CHEMBL940169) |
|---|
| Ki | 38300±n/a nM |
|---|
| Citation |  Fedorov, O; Marsden, B; Pogacic, V; Rellos, P; Müller, S; Bullock, AN; Schwaller, J; Sundström, M; Knapp, S A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proc Natl Acad Sci U S A104:20523-8 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Casein kinase I isoform alpha |
|---|
| Name: | Casein kinase I isoform alpha |
|---|
| Synonyms: | CK1 | CKI-alpha | CSNK1A1 | Casein Kinase I | Casein kinase 1 alpha (CK1 alpha) | Casein kinase I isoform alpha/delta | KC1A_HUMAN |
|---|
| Type: | Serine/threonine-protein kinase |
|---|
| Mol. Mass.: | 38936.59 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P48729 |
|---|
| Residue: | 337 |
|---|
| Sequence: | MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
LKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF
|
|
|
|---|
| BDBM15211 |
|---|
| n/a |
|---|
| Name | BDBM15211 |
|---|
| Synonyms: | CHEMBL104264 | H-89 | H89 | HT-89 (H-89) | N-(2-{[(2E)-3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide | N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H20BrN3O2S |
|---|
| Mol. Mass. | 446.361 |
|---|
| SMILES | Brc1ccc(\C=C\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
