| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50021959 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_474299 (CHEMBL936078) |
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| IC50 | 70±n/a nM |
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| Citation |  Papagiannitsis, CC; Loli, A; Tzouvelekis, LS; Tzelepi, E; Arlet, G; Miriagou, V SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli. Antimicrob Agents Chemother51:2185-8 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta-lactamase SCO-1 | SCO-1 carbenicillinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30647.09 |
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| Organism: | Escherichia coli |
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| Description: | ChEMBL_474299 |
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| Residue: | 288 |
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| Sequence: | MTRSALLIPLTTAAIALNAISPVYASDTHSIDDTVKQVETTLGAKVGIAVLDTGSQRAWF
HRADDRFPMASTSKALTCAALLDKGQSFMNKEALIKKADLDEYAPVTSGIVGKKVSAADL
CSITMRTSDNTAVNKVLEILGGPQAVTAYLRKTGDNITRLDRNEPDLNEGTPGDVRDTTT
PRAILETLNKLVLGPTLGSDERKQLTTWLESNEVGDPLLRAGVPSDWRVADRTGAGGNGT
RGVIAVMWPPKHAPIIAAIYITQTKATMEERNAAIASIGKAIAAEVLE
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| BDBM50021959 |
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| n/a |
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| Name | BDBM50021959 |
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| Synonyms: | CHEMBL777 | MM 14151 | US9120808, Clavulanic acid potassium salt | antibiotic MM 14151 | clavulanic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C8H9NO5 |
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| Mol. Mass. | 199.1608 |
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| SMILES | OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O |r| |
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| Structure | 
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