| Reaction Details |
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 | Report a problem with these data |
| Target | RmtA |
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| Ligand | BDBM50376141 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_475539 (CHEMBL925748) |
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| IC50 | 89700±n/a nM |
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| Citation |  Mai, A; Cheng, D; Bedford, MT; Valente, S; Nebbioso, A; Perrone, A; Brosch, G; Sbardella, G; De Bellis, F; Miceli, M; Altucci, L epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors. J Med Chem51:2279-90 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| RmtA |
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| Name: | RmtA |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39351.26 |
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| Organism: | Emericella nidulans |
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| Description: | ChEMBL_475539 |
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| Residue: | 345 |
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| Sequence: | MSEIENSTITSSADRMVGMDHAEVRYFTSYDHHGIHEEMLKDDVRTRSYRDSIYQNRHIF
KDKVVLDVGCGTGILSMFAAKAGAKHVIGVDMSSIIEKAREIVAVNGLADKITLLQGKME
EVQLPFPSVDIIISEWMGYFLLYESMLDTVLYAQDRYLVPGGKIFPDKATMYLAGIEDGE
YKDDKIGFWDNVYGFDYSPMKEIALTEPLVDTVELKALVTDPCPIITFDLYTVTKEDLAF
EVPYSLPVKRSDFVHAVIAWFDIEFGACHKPINFSTGPHAKYTHWKQTVFYLRDVLTVEE
EESISGVLSNRPNDKNKRDLDINLTYKLETQDQTRFAEGGCFYRM
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| BDBM50376141 |
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| n/a |
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| Name | BDBM50376141 |
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| Synonyms: | CHEMBL261192 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12Br4N2O4 |
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| Mol. Mass. | 615.893 |
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| SMILES | Oc1c(Br)cc(cc1Br)C(=O)NCCNC(=O)c1cc(Br)c(O)c(Br)c1 |
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| Structure | 
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